Source:http://linkedlifedata.com/resource/pubmed/id/19117487
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-1-29
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pubmed:abstractText |
Inspired by the common skeletal motifs of Ca(2+)-ATPases inhibitors involving artemisinin and transtaganolide D, small molecule collections with the three-dimensional structural diversity of tricyclic systems were designed and expeditiously synthesized (4-5 steps). A synthetic strategy featuring stereochemical diversification of ring-junctions and control of cyclization modes was devised to access varied molecular architectures in a systematic fashion.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1523-7052
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-4
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pubmed:meshHeading | |
pubmed:year |
2009
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pubmed:articleTitle |
Skeletal and stereochemical diversification of tricyclic frameworks inspired by Ca(2+)-ATPase inhibitors, artemisinin and transtaganolide D.
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pubmed:affiliation |
Division of Chemistry, Graduate School of Science, and Division of Innovative Research, Hokkaido University, N21, W10, Sapporo 001-0021, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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