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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0029408,
umls-concept:C0035820,
umls-concept:C0127400,
umls-concept:C0185117,
umls-concept:C0331858,
umls-concept:C0332120,
umls-concept:C0443199,
umls-concept:C1363844,
umls-concept:C1704640,
umls-concept:C1706515,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-12
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pubmed:abstractText |
Alpha B-crystallin belongs to the family of small heat-shock proteins (HSPs). The role of this protein family in chondrocytes is not well understood. The present study was undertaken to investigate expression levels of alphaB-crystallin in chondrocytes isolated from healthy subjects and patients with osteoarthritis (OA), and to explore the functional role of this potentially interesting protein in chondrocyte metabolism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-88
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pubmed:meshHeading |
pubmed-meshheading:19116904-Adult,
pubmed-meshheading:19116904-Aged,
pubmed-meshheading:19116904-Blotting, Western,
pubmed-meshheading:19116904-Cell Differentiation,
pubmed-meshheading:19116904-Cells, Cultured,
pubmed-meshheading:19116904-Chondrocytes,
pubmed-meshheading:19116904-Extracellular Matrix,
pubmed-meshheading:19116904-Female,
pubmed-meshheading:19116904-Gene Expression,
pubmed-meshheading:19116904-Humans,
pubmed-meshheading:19116904-Interleukin-1beta,
pubmed-meshheading:19116904-Male,
pubmed-meshheading:19116904-Middle Aged,
pubmed-meshheading:19116904-Osteoarthritis, Knee,
pubmed-meshheading:19116904-Phosphorylation,
pubmed-meshheading:19116904-Proteomics,
pubmed-meshheading:19116904-RNA, Small Interfering,
pubmed-meshheading:19116904-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19116904-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19116904-alpha-Crystallin B Chain
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pubmed:year |
2009
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pubmed:articleTitle |
Differential expression of alphaB-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis.
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pubmed:affiliation |
Ghent University, Ghent, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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