Linked Life Data

19112833

Source:http://linkedlifedata.com/resource/pubmed/id/19112833

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
147
pubmed:dateCreated
2008-12-30
pubmed:abstractText
Cardiovascular disease is the most common cause of a high morbidity and mortality in patients on renal replacement therapy and is responsible for about 50% of deaths. Hypertension is the main risk factor for cardiovascular events in the general population as well as in haemodialysed (HD) patients. The hypertension in HD patients is caused by excess extracellular fluid volume (ECV) on the other hand hypertension resistant to normalization of ECV may result from the accelerated activity of the systemic and local--vascular renin-angiotensin-aldosteron system (RAAS). RAAS genes are potential etiological candidates for cardiovascular damage. The aim of the study was to evaluate the prevalence of hypertension, left ventricular hypertrophy, hypertensive retinopathy in patients treated with haemodialysis and to evaluate the association between the polymorphism of RAAS genes: ACE I/D, AGT M235T AT1R A1166C, CYP112 (-344) and the systemic complications of arterial hypertension such as hypertensive retinopathy, left ventricular hypertrophy and also mortality in haemodialysis patients.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1426-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-16
pubmed:dateRevised
2011-7-1
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[Genetic predisposition to systemic complications of arterial hypertension in maintenance haemodialysis patients].
pubmed:affiliation
Klinika Nefrologii, Transplantologii i Chorób Wewnetrznych. bbzoma@mp.pl
pubmed:publicationType
Journal Article, English Abstract