Source:http://linkedlifedata.com/resource/pubmed/id/19112029
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-3-23
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pubmed:abstractText |
The design and implementation of a radio frequency acoustic desorption ionization (RADIO) source has been demonstrated for the analysis of multiply charged peptides and proteins. One muL aliquots of melittin, BNP-32, and ubiquitin ( approximately 1 mug of analyte) were deposited onto a quartz crystal microbalance (QCM) electrode before radio frequency actuation for desorption. Continuous electrospray parallel to/above the sampling surface enabled the ionization of desorbed species. Detection by a hybrid linear ion trap Fourier transform ion cyclotron resonance mass spectrometer confirmed the intact and dissociated species observed during MS and MS/MS experiments, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Natriuretic Peptide, Brain,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Quartz,
http://linkedlifedata.com/resource/pubmed/chemical/Ubiquitin
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1879-1123
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
597-600
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pubmed:meshHeading |
pubmed-meshheading:19112029-Electrodes,
pubmed-meshheading:19112029-Equipment Design,
pubmed-meshheading:19112029-Mass Spectrometry,
pubmed-meshheading:19112029-Natriuretic Peptide, Brain,
pubmed-meshheading:19112029-Peptides,
pubmed-meshheading:19112029-Proteins,
pubmed-meshheading:19112029-Quartz,
pubmed-meshheading:19112029-Ubiquitin
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pubmed:year |
2009
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pubmed:articleTitle |
Generation of multiply charged peptides and proteins by radio frequency acoustic desorption and ionization for mass spectrometric detection.
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pubmed:affiliation |
W. M. Keck FT-ICR Mass Spectrometry Laboratory, Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27695, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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