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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-12-26
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pubmed:abstractText |
The mechanisms of granulocytopoiesis stimulation with granulocytic CSF (neupogen), added to chemotherapy protocol (adriablastine+taxotere) in patients with stages III-IV breast cancer, were studied. The hemostimulatory effect of granulocytic CSF preparation is based on stimulation of proliferation and differentiation of granulomonocytopoisis precursor cell in the hemopoietic tissue, due to neupogen effects on hemopoietic elements and on the hemopoiesis-inducing microenvironment cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0007-4888
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
467-71
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19110596-Adult,
pubmed-meshheading:19110596-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19110596-Breast Neoplasms,
pubmed-meshheading:19110596-Cell Differentiation,
pubmed-meshheading:19110596-Cell Proliferation,
pubmed-meshheading:19110596-Cells, Cultured,
pubmed-meshheading:19110596-Doxorubicin,
pubmed-meshheading:19110596-Female,
pubmed-meshheading:19110596-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:19110596-Granulocytes,
pubmed-meshheading:19110596-Hematopoiesis,
pubmed-meshheading:19110596-Humans,
pubmed-meshheading:19110596-Middle Aged,
pubmed-meshheading:19110596-Recombinant Proteins,
pubmed-meshheading:19110596-Taxoids,
pubmed-meshheading:19110596-Treatment Outcome,
pubmed-meshheading:19110596-Up-Regulation
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pubmed:year |
2008
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pubmed:articleTitle |
Mechanisms of stimulation of granulocytopoiesis with neupogen in patients with breast cancer during chemotherapy.
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pubmed:affiliation |
Institute of Pharmacology and Institute of Oncology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Russia.
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pubmed:publicationType |
Journal Article,
Controlled Clinical Trial
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