Linked Life Data

19108448

Source:http://linkedlifedata.com/resource/pubmed/id/19108448

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2008-12-25
pubmed:abstractText
Bone metastases is a serious complication of patients with tumor. It is associated with substantial morbidity, including bone pain, pathological fracture,neurological deficit and (or) hypercalcemia. Thus, the management of bone metastasis is a clinically significant issue. Bisphosphonates have now become a part of standard therapy to treat and prevent skeletal-related events (SRE), it could inhibit osteoclast-mediated bone resorption and demonstrate antitumor activity in preclinical models. Bisphosphonates are the most effective agent for treating and (or) preventing complications of bone metastasis, reducing the incidence of skeletal-related events, and improving quality of life in patients with bone metastasis.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1003-0034
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
480-2
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
[The application advances of bisphosphonates in bone metastasis].
pubmed:affiliation
Department of Orthopaedics, the Gansu Cancer Hospital, Lanzhou 730050, Gansu, China. liangplz0801@hotmail.com
pubmed:publicationType
Journal Article, English Abstract, Review