19107951

Source:http://linkedlifedata.com/resource/pubmed/id/19107951

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007137, umls-concept:C0009429, umls-concept:C0021467, umls-concept:C0021469, umls-concept:C0144576, umls-concept:C0460004, umls-concept:C0556895, umls-concept:C0599894, umls-concept:C1420466, umls-concept:C1521840
pubmed:issue	5
pubmed:dateCreated	2009-4-13
pubmed:abstractText	Aurora kinase A (AURKA) is amplified with varying incidence in multiple human cancers including head and neck squamous cell carcinoma (HNSCC). We investigated whether AURKA is a potential therapeutic target in HNSCC.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/1P50-CA-97007, http://linkedlifedata.com/resource/pubmed/grant/5P30 CA16672, http://linkedlifedata.com/resource/pubmed/grant/R01 CA89716, http://linkedlifedata.com/resource/pubmed/grant/R01 DE-13954, http://linkedlifedata.com/resource/pubmed/grant/R01 DE013954-05
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8902541
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, Phytogenic, http://linkedlifedata.com/resource/pubmed/chemical/Paclitaxel, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering, http://linkedlifedata.com/resource/pubmed/chemical/aurora kinase
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1097-0347
pubmed:author	pubmed-author:ClaymanGary LGL, pubmed-author:El-NaggarAdel KAK, pubmed-author:HendersonYing CYC, pubmed-author:MazumdarAbhijitA, pubmed-author:SenSubrataS
pubmed:issnType	Electronic
pubmed:volume	31
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	625-34
pubmed:dateRevised	2011-7-11
pubmed:meshHeading	pubmed-meshheading:19107951-Antineoplastic Agents, Phytogenic, pubmed-meshheading:19107951-Apoptosis, pubmed-meshheading:19107951-Blotting, Western, pubmed-meshheading:19107951-Carcinoma, Squamous Cell, pubmed-meshheading:19107951-Cell Proliferation, pubmed-meshheading:19107951-Flow Cytometry, pubmed-meshheading:19107951-G1 Phase, pubmed-meshheading:19107951-Gene Knockdown Techniques, pubmed-meshheading:19107951-Head and Neck Neoplasms, pubmed-meshheading:19107951-Humans, pubmed-meshheading:19107951-Immunohistochemistry, pubmed-meshheading:19107951-Paclitaxel, pubmed-meshheading:19107951-Protein-Serine-Threonine Kinases, pubmed-meshheading:19107951-RNA, Messenger, pubmed-meshheading:19107951-RNA, Small Interfering, pubmed-meshheading:19107951-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:19107951-Transfection, pubmed-meshheading:19107951-Tumor Cells, Cultured
pubmed:year	2009
pubmed:articleTitle	Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma.
pubmed:affiliation	Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural