rdf:type |
|
lifeskim:mentions |
umls-concept:C0005516,
umls-concept:C0009924,
umls-concept:C0017262,
umls-concept:C0021968,
umls-concept:C0022646,
umls-concept:C0034693,
umls-concept:C0185117,
umls-concept:C0185125,
umls-concept:C0333117,
umls-concept:C1883709,
umls-concept:C2911684
|
pubmed:issue |
2
|
pubmed:dateCreated |
2009-2-25
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pubmed:abstractText |
Commercially available iodinated contrast media (CM) show significantly different physico-chemical properties. The relevance of the viscosity of CM may be underestimated as a contributing factor for clinically relevant renal failure as suggested by a large registry data analysis (Swedish registry study). The objective of this preclinical study is to assess differences of a low and high-viscous CM regarding their retention time in the kidney. Furthermore, we investigated the expression of marker genes for renal damage and hypoxia to evaluate a potential renal damage and hypoxia after application of iodinated CM.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/Contrast Media,
http://linkedlifedata.com/resource/pubmed/chemical/Havcr1protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Heme Oxygenase (Decyclizing),
http://linkedlifedata.com/resource/pubmed/chemical/Hmox1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Iohexol,
http://linkedlifedata.com/resource/pubmed/chemical/Triiodobenzoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/iodixanol,
http://linkedlifedata.com/resource/pubmed/chemical/iopromide
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
1536-0210
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
114-23
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:19104440-Animals,
pubmed-meshheading:19104440-Cell Adhesion Molecules,
pubmed-meshheading:19104440-Contrast Media,
pubmed-meshheading:19104440-Dose-Response Relationship, Drug,
pubmed-meshheading:19104440-Heme Oxygenase (Decyclizing),
pubmed-meshheading:19104440-Iohexol,
pubmed-meshheading:19104440-Kidney,
pubmed-meshheading:19104440-Kidney Diseases,
pubmed-meshheading:19104440-Rats,
pubmed-meshheading:19104440-Rats, Wistar,
pubmed-meshheading:19104440-Triiodobenzoic Acids
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pubmed:year |
2009
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pubmed:articleTitle |
Retention of iodine and expression of biomarkers for renal damage in the kidney after application of iodinated contrast media in rats.
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pubmed:affiliation |
TRG Diagnostic Imaging, Bayer Schering Pharma AG, Berlin, Germany.
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pubmed:publicationType |
Journal Article
|