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rdf:type |
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lifeskim:mentions |
umls-concept:C0012373,
umls-concept:C0086418,
umls-concept:C0334094,
umls-concept:C0681850,
umls-concept:C0871261,
umls-concept:C1321301,
umls-concept:C1533691,
umls-concept:C1550501,
umls-concept:C1704632,
umls-concept:C1706203,
umls-concept:C1706817,
umls-concept:C1707455,
umls-concept:C1709059,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2911692
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-23
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pubmed:abstractText |
The gradual aging of population has increased the number of elderly patients receiving kidney transplants. In elderly transplant recipients, careful immunosuppression has to be maintained to avoid both rejection and adverse effects. Clinical protocols after kidney transplantation include use of the calcium channel antagonist diltiazem to ameliorate the hypertensive effect and nephrotoxicity of the immunosuppressant agent ciclosporin (cyclosporine).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD3,
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclosporine,
http://linkedlifedata.com/resource/pubmed/chemical/Diltiazem,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/Pokeweed Mitogens,
http://linkedlifedata.com/resource/pubmed/chemical/Tuberculin
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pubmed:status |
MEDLINE
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pubmed:issn |
1170-229X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-94
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pubmed:meshHeading |
pubmed-meshheading:19102517-Adult,
pubmed-meshheading:19102517-Age Factors,
pubmed-meshheading:19102517-Aged,
pubmed-meshheading:19102517-Aging,
pubmed-meshheading:19102517-Antibodies, Monoclonal,
pubmed-meshheading:19102517-Antigens, CD3,
pubmed-meshheading:19102517-Antihypertensive Agents,
pubmed-meshheading:19102517-Cell Proliferation,
pubmed-meshheading:19102517-Cyclosporine,
pubmed-meshheading:19102517-Diltiazem,
pubmed-meshheading:19102517-Dose-Response Relationship, Drug,
pubmed-meshheading:19102517-Female,
pubmed-meshheading:19102517-Humans,
pubmed-meshheading:19102517-Immunosuppressive Agents,
pubmed-meshheading:19102517-Interleukin-2,
pubmed-meshheading:19102517-Leukocytes, Mononuclear,
pubmed-meshheading:19102517-Male,
pubmed-meshheading:19102517-Middle Aged,
pubmed-meshheading:19102517-Pokeweed Mitogens,
pubmed-meshheading:19102517-Tuberculin,
pubmed-meshheading:19102517-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Modulation of human peripheral blood mononuclear cell proliferative response by diltiazem : in vitro comparison in younger versus older subjects.
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pubmed:affiliation |
Department of Infectious, Parasitic and Immuno-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy. antonella.dambrosio@iss.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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