Source:http://linkedlifedata.com/resource/pubmed/id/19100645
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2009-2-11
|
| pubmed:abstractText |
It was the goal of the trial to assess cardiovascular risk factors in children and adolescents with type 1 diabetes mellitus or overweight/obesity. All children and adolescents (n=77 [n=45 patients with diabetes mellitus, n=32 patients with overweight/obesity]) admitted to our hospital during the period from 01/07 to 31/08/2006 were included in the trial. Socio-demographic and laboratory data (age, sex, diabetes duration, BMI, BMI-SDS, HbA1c, fasting blood glucose, oGTT in patients with overweight/obesity, lipids, CRP, TSH, creatinine, and microalbuminuria) were assessed. The diameter of a retinal arterial and a venous segment was measured continuously on-line with a Dynamic Vessel Analyzer, carotid intima-media thickness (IMT) was measured, and 24-h-blood pressure monitoring was applied. RESULTS: Flicker light stimulation induces a comparable arterial dilatation in patients with type 1 diabetes and overweight/obesity. Univariate ANOVA in patients with type 1 diabetes shows an influence of diastolic blood pressure on arterial dilatation. Other factors such as BMI, age, diabetes duration, smoking, sex, HbA1c and insulin dose/kg had no effect. CONCLUSIONS: In children and adolescents with diabetes or overweight/obesity retinal vascular alterations seem to be more sensitive and already present before the occurrence of classic cardiovascular markers.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
1872-8227
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
83
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
358-64
|
| pubmed:meshHeading |
pubmed-meshheading:19100645-Adolescent,
pubmed-meshheading:19100645-Albuminuria,
pubmed-meshheading:19100645-Blood Pressure,
pubmed-meshheading:19100645-Body Height,
pubmed-meshheading:19100645-Body Mass Index,
pubmed-meshheading:19100645-Child,
pubmed-meshheading:19100645-Cross-Sectional Studies,
pubmed-meshheading:19100645-Diabetes Mellitus, Type 1,
pubmed-meshheading:19100645-Diagnostic Techniques, Ophthalmological,
pubmed-meshheading:19100645-Female,
pubmed-meshheading:19100645-Humans,
pubmed-meshheading:19100645-Male,
pubmed-meshheading:19100645-Obesity,
pubmed-meshheading:19100645-Overweight,
pubmed-meshheading:19100645-Photic Stimulation,
pubmed-meshheading:19100645-Retinal Vein,
pubmed-meshheading:19100645-Retinal Vessels,
pubmed-meshheading:19100645-Vasodilation,
pubmed-meshheading:19100645-Visual Acuity
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Retinal vessel response to flicker light in children and adolescents with type 1 diabetes mellitus and overweight or obesity.
|
| pubmed:affiliation |
MEDIGREIF-Inselklinik Heringsdorf GmbH, Department of Diabetes and Metabolic Diseases, Setheweg 11, D-17424 Seeheilbad Heringsdorf, Germany. inselklinik.schiel@medigreif.de
|
| pubmed:publicationType |
Journal Article
|