Source:http://linkedlifedata.com/resource/pubmed/id/19097149
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rdf:type | |
lifeskim:mentions |
umls-concept:C0021102,
umls-concept:C0038126,
umls-concept:C0040302,
umls-concept:C0076732,
umls-concept:C0115137,
umls-concept:C0205148,
umls-concept:C0290219,
umls-concept:C0527496,
umls-concept:C0656820,
umls-concept:C0661800,
umls-concept:C1515655,
umls-concept:C1521828,
umls-concept:C1522492,
umls-concept:C1533691,
umls-concept:C1707520
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pubmed:issue |
4
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pubmed:dateCreated |
2009-11-12
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pubmed:abstractText |
The rate of bony ingrowth to identical metal implants made of either pure titanium (cpTi), titanium alloy (Ti-6Al-4V), or stainless steel 316L (SS) inserted to the medullar canal of the femur in rats was investigated. The kinetics of spontaneous deposition of hydroxyapatite (HA) globules on the aforementioned metals in vitro during incubation in simulated body fluid (SBF) was also studied. It was found that the rate of increased bonding strength between the cpTi implants and the host bone was the highest, whereas around the SS implants it was the slowest. At 10 days postimplant insertion, the shear strength of the cpTi implants was 2.2- and 4-fold significantly higher than for the Ti-6Al-4V and the SS implants, respectively. Spontaneous formation of the HA globules on the cpTi and Ti-6Al-4V implants that were incubated in the SBF was observed as early as 6 and 10 days after incubation in SBF, respectively, whereas on SS implants, deposition of HA was evident only after 2 weeks of in vitro incubation in SBF. It is concluded that the chemical surface characteristics and the biocompatibility of the implants probably play a key role in the process of bone growth next to them, during the formation of bone in vivo. The rate of bony ingrowth to various metal implants alloys inserted into the medullar canal of rats correlates well with the induction of apatite formation on them during incubation in vitro with SBF.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1552-4965
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1006-9
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pubmed:meshHeading |
pubmed-meshheading:19097149-Animals,
pubmed-meshheading:19097149-Bone Development,
pubmed-meshheading:19097149-Durapatite,
pubmed-meshheading:19097149-Implants, Experimental,
pubmed-meshheading:19097149-Kinetics,
pubmed-meshheading:19097149-Microscopy, Electron, Scanning,
pubmed-meshheading:19097149-Rats,
pubmed-meshheading:19097149-Rats, Sprague-Dawley,
pubmed-meshheading:19097149-Shear Strength,
pubmed-meshheading:19097149-Stainless Steel,
pubmed-meshheading:19097149-Surface Properties,
pubmed-meshheading:19097149-Titanium
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pubmed:year |
2009
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pubmed:articleTitle |
Correlation between rate of bony ingrowth to stainless steel, pure titanium, and titanium alloy implants in vivo and formation of hydroxyapatite on their surfaces in vitro.
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pubmed:affiliation |
Department of Orthopedics A, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Zerifin 70300, Israel. amiroronmd@gmail.com
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pubmed:publicationType |
Journal Article
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