Source:http://linkedlifedata.com/resource/pubmed/id/19096892
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2009-2-13
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| pubmed:abstractText |
Treatment of extensive diffuse pigmented villonodular synovitis (PVNS) of large joints by isolated surgical resection is unsatisfactory, with high rates of local recurrence. Post-synovectomy adjuvant treatment with external beam radiation therapy or intra-articular injection of radioactive material as yttrium-90 ((90)Y) yielded better results. Between January 2005 and January 2007, 12 patients (eight men and four women aged 19-49 years) with extensive diffuse PVNS of the knee were treated. All patients had an adjuvant post-operative external beam radiation therapy (2,600-3,000 cGy) conventionally fractionated 200 cGy/fraction, five fractions/week, 6-8 weeks after surgery. Mean follow-up time was 27 months (range from 20 to 36 months). All patients were followed up using clinical assessment, magnetic resonance imaging, and plain X-ray. In all patients, neither evidence of disease recurrence nor progression of bone or articular destruction was noted. No complications were noticed after surgery or after post-operative external beam radiation therapy. A combination of debulking surgery using anterior and posterior approach with adjuvant post-operative external beam radiation therapy for extensive diffuse PVNS of the knee joint is a reliable treatment method, with good results in regard to the incidence of local recurrence and functional outcome.
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| pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-10683884,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-12364629,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-1748702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-1985707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-2559664,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-2791393,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-3597511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-6317696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-6332499,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-7863772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-8425352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-8633118,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19096892-8780753
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:month |
Feb
|
| pubmed:issn |
1556-3316
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
5
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
19-23
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| pubmed:dateRevised |
2010-9-23
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| pubmed:year |
2009
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| pubmed:articleTitle |
Treatment of diffuse pigmented villonodular synovitis of the knee with combined surgical and radiosynovectomy.
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| pubmed:affiliation |
Orthopaedic Department, Ain Shams University, Demerdash Hospital, Abbasseia Square, Cairo, Egypt. wgnassar@hotmail.com
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| pubmed:publicationType |
Journal Article
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