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19096081
Source:
http://linkedlifedata.com/resource/pubmed/id/19096081
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0021368
,
umls-concept:C0026809
,
umls-concept:C0033414
,
umls-concept:C0041956
,
umls-concept:C0151650
,
umls-concept:C0205092
,
umls-concept:C0332453
,
umls-concept:C1334470
pubmed:issue
5
pubmed:dateCreated
2009-4-15
pubmed:abstractText
The present study tested the hypothesis that disruption of Smad7 function may accelerate renal fibrosis and inflammation.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/8706402
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B
,
http://linkedlifedata.com/resource/pubmed/chemical/Smad2 Protein
,
http://linkedlifedata.com/resource/pubmed/chemical/Smad2 protein, mouse
,
http://linkedlifedata.com/resource/pubmed/chemical/Smad3 Protein
,
http://linkedlifedata.com/resource/pubmed/chemical/Smad3 protein, mouse
,
http://linkedlifedata.com/resource/pubmed/chemical/Smad7 Protein
,
http://linkedlifedata.com/resource/pubmed/chemical/Smad7 protein, mouse
,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
,
http://linkedlifedata.com/resource/pubmed/chemical/eIF-2 Kinase
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1460-2385
pubmed:author
pubmed-author:ChungArthur C KAC
,
pubmed-author:HeuchelRainerR
,
pubmed-author:HuangXiao RXR
,
pubmed-author:LaiKar NengKN
,
pubmed-author:LanHui YHY
,
pubmed-author:ZhouLiL
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1443-54
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:19096081-Animals
,
pubmed-meshheading:19096081-Disease Models, Animal
,
pubmed-meshheading:19096081-Fibrosis
,
pubmed-meshheading:19096081-Inflammation
,
pubmed-meshheading:19096081-Kidney
,
pubmed-meshheading:19096081-Mice
,
pubmed-meshheading:19096081-Mice, Knockout
,
pubmed-meshheading:19096081-NF-kappa B
,
pubmed-meshheading:19096081-Signal Transduction
,
pubmed-meshheading:19096081-Smad2 Protein
,
pubmed-meshheading:19096081-Smad3 Protein
,
pubmed-meshheading:19096081-Smad7 Protein
,
pubmed-meshheading:19096081-Transforming Growth Factor beta
,
pubmed-meshheading:19096081-Ureteral Obstruction
,
pubmed-meshheading:19096081-eIF-2 Kinase
pubmed:year
2009
pubmed:articleTitle
Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice.
pubmed:affiliation
Department of Medicine, The University of Hong Kong, Li Ka Shing Faculty of Medicine, Hong Kong, China.
pubmed:publicationType
Journal Article
,
Research Support, Non-U.S. Gov't