| pubmed-article:1909049 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0005821 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0031676 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0015689 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0133860 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0012180 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C0243126 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:1909049 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:1909049 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:1909049 | pubmed:dateCreated | 1991-10-3 | lld:pubmed |
| pubmed-article:1909049 | pubmed:abstractText | The effect of a high dietary intake of n-6 fatty acids (36 g daily) vs a low intake (4-6 g daily) on the incorporation of fatty acids from a dietary supplementation of n-3 fatty acids (6 g daily) was studied for 8 weeks in 15 healthy, normolipaemic volunteers. The importance of a high (43.6) vs a low (20.6) energy percentage from fat was also investigated in the participants on a low n-6 intake. Fatty acid analyses of serum and thrombocyte phospholipids showed a marked increase in docosahexaenoic acid (22:6 (n-3), DHA) and especially eicosapentaenoic acid (20:5 (n-3), EPA) in both the high and low n-6 groups after 14 days, but the changes were significantly greater in the low n-6 diet groups. Changes of the ratio between EPA and arachidonic acid (20:4 (n-6), AA) in phospholipids followed an identical pattern in serum and thrombocytes. This indicates that thrombocytes are influenced by the fatty acid composition in serum. The results showed that incorporation of n-3 fatty acids in phospholipids was reduced by a high intake of dietary n-6 fatty acids in the cells and lipid fractions studied. The observed effect of dietary n-6 fatty acids was independent of the energy percentage provided by dietary fat. In order to obtain an optimal effect of n-3 supplementation, the intake of linoleic acid has to be considered and kept at a low level. The serum content of cholesterol was unaffected, but the concentration of triacylglycerol was reduced during the supplementation period. | lld:pubmed |
| pubmed-article:1909049 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1909049 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1909049 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1909049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1909049 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1909049 | pubmed:month | May | lld:pubmed |
| pubmed-article:1909049 | pubmed:issn | 0036-5513 | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:OseLL | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:ChristensenEE | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:GrønnMM | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:Christopherse... | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:HagveT ATA | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:LevorsenAA | lld:pubmed |
| pubmed-article:1909049 | pubmed:author | pubmed-author:GørbitzCC | lld:pubmed |
| pubmed-article:1909049 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1909049 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:1909049 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1909049 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1909049 | pubmed:pagination | 255-63 | lld:pubmed |
| pubmed-article:1909049 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1909049 | pubmed:meshHeading | pubmed-meshheading:1909049-... | lld:pubmed |
| pubmed-article:1909049 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1909049 | pubmed:articleTitle | Dietary n-6 fatty acids inhibit the incorporation of dietary n-3 fatty acids in thrombocyte and serum phospholipids in humans: a controlled dietetic study. | lld:pubmed |
| pubmed-article:1909049 | pubmed:affiliation | Institute of Clinical Biochemistry, Rikshospitalet, Oslo, Norway. | lld:pubmed |
| pubmed-article:1909049 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1909049 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1909049 | lld:pubmed |
