Source:http://linkedlifedata.com/resource/pubmed/id/19088172
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-3-26
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pubmed:abstractText |
Mutations of the epidermal growth factor receptor (EGFR) gene in non-small-cell lung cancer (NSCLC) patients predict the patients who will respond to EGFR tyrosine kinase inhibitor (TKI) treatment. A recent study has suggested that 33% of NSCLC showed primary tumor/metastasis discordance of EGFR expression by immunohistochemistry analysis. We intended to find out whether the EGFR mutations of primary lung cancers are concordant to that of corresponding metastatic tumors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1569-8041
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
696-702
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19088172-Adult,
pubmed-meshheading:19088172-Aged,
pubmed-meshheading:19088172-Aged, 80 and over,
pubmed-meshheading:19088172-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:19088172-Exons,
pubmed-meshheading:19088172-Female,
pubmed-meshheading:19088172-Humans,
pubmed-meshheading:19088172-Lung Neoplasms,
pubmed-meshheading:19088172-Male,
pubmed-meshheading:19088172-Middle Aged,
pubmed-meshheading:19088172-Mutation,
pubmed-meshheading:19088172-Neoplasm Metastasis,
pubmed-meshheading:19088172-Protein Kinase Inhibitors,
pubmed-meshheading:19088172-Protein-Tyrosine Kinases,
pubmed-meshheading:19088172-Receptor, Epidermal Growth Factor
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pubmed:year |
2009
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pubmed:articleTitle |
Comparison of epidermal growth factor receptor mutations between primary and corresponding metastatic tumors in tyrosine kinase inhibitor-naive non-small-cell lung cancer.
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pubmed:affiliation |
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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