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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1991-9-24
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pubmed:abstractText |
Between January 1977 and March 1991, 86 patients of Stage III and Stage IV breast cancer were treated by intra-arterial infusion chemotherapy (IAIC) in Sapporo Medical College. The 5- and 10-year overall survival rates of Stage III b were: infusion group 53.1% and 53.1%, non infusion group 50.1% and 16.7%, respectively. A significant difference was seen in the 10-year survival rate (p less than 0.05). The 5- and 10-year overall survival rate of Stage III b histologically effective group was 67.3% and non-effective group 31.8%. A significant difference was seen between these two groups (p = 0.0241). A significant difference was seen between n2 positive Stage III b infusion group and non-infusion group in 7-year survival rate (p less than 0.01). The ischemic effect on tumor cells by degeneration changes of the blood vessels was important for the histological effect. Pre-operative angiography helped in the choice of anticancer agents. The sufficient adjuvant chemo-endocrine therapy will assure a good prognosis for IAIC-treated Stage III b breast cancer patients.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0385-0684
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
1735-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1908650-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1908650-Breast Neoplasms,
pubmed-meshheading:1908650-Doxorubicin,
pubmed-meshheading:1908650-Female,
pubmed-meshheading:1908650-Fluorouracil,
pubmed-meshheading:1908650-Humans,
pubmed-meshheading:1908650-Infusions, Intra-Arterial,
pubmed-meshheading:1908650-Life Tables,
pubmed-meshheading:1908650-Lymphatic Metastasis,
pubmed-meshheading:1908650-Mitomycin,
pubmed-meshheading:1908650-Mitomycins,
pubmed-meshheading:1908650-Neoplasm Staging,
pubmed-meshheading:1908650-Prognosis,
pubmed-meshheading:1908650-Survival Rate
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pubmed:year |
1991
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pubmed:articleTitle |
[Effect, recurrence and prognosis of intra-arterial infusion chemotherapy with anticancer agents for advanced breast cancer--especially, the significance of tumor blood vessels].
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pubmed:affiliation |
1st Dept. of Surgery, Sapporo Medical College.
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pubmed:publicationType |
Journal Article,
English Abstract
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