Source:http://linkedlifedata.com/resource/pubmed/id/19082148
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19
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pubmed:dateCreated |
2008-12-16
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pubmed:abstractText |
Gamma-turn analogues comprising a modified dipeptide constrained in an eleven-membered ring were prepared by alkene metathesis and analysed by NMR and molecular modelling studies. The results reveal that some of the cyclic analogues form inverse gamma-turns and preferentially adopt conformations determined by the identity of the incorporated amino acid residues and the nature of the constraining linker (E/Z-alkene or alkane).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1477-0539
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
7
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3476-85
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pubmed:meshHeading |
pubmed-meshheading:19082148-Alkenes,
pubmed-meshheading:19082148-Carboxylic Acids,
pubmed-meshheading:19082148-Dipeptides,
pubmed-meshheading:19082148-Magnetic Resonance Spectroscopy,
pubmed-meshheading:19082148-Models, Molecular,
pubmed-meshheading:19082148-Molecular Conformation,
pubmed-meshheading:19082148-Peptides, Cyclic,
pubmed-meshheading:19082148-Stereoisomerism
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pubmed:year |
2008
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pubmed:articleTitle |
Synthesis and conformational analysis of cyclic analogues of inverse gamma-turns.
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pubmed:affiliation |
Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford, UK OX1 3TA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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