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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-2-10
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pubmed:abstractText |
A T(H)1-specific transcription factor, T-box-containing protein expressed in T cells (T-bet), controls the production of both T(H)1 and T(H)2 cytokines in T(H) cell differentiation by means of distinct mechanisms. T-bet-deficient mice overproduce T(H)2 cytokines and have spontaneous airway inflammation.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1097-6825
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
479-85
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pubmed:meshHeading |
pubmed-meshheading:19081613-Allergens,
pubmed-meshheading:19081613-Animals,
pubmed-meshheading:19081613-Asthma,
pubmed-meshheading:19081613-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:19081613-Cytokines,
pubmed-meshheading:19081613-Disease Models, Animal,
pubmed-meshheading:19081613-Doxycycline,
pubmed-meshheading:19081613-Eosinophilia,
pubmed-meshheading:19081613-Goblet Cells,
pubmed-meshheading:19081613-Immunoglobulin E,
pubmed-meshheading:19081613-Mice,
pubmed-meshheading:19081613-Mice, Inbred C57BL,
pubmed-meshheading:19081613-Mice, Knockout,
pubmed-meshheading:19081613-Mice, Transgenic,
pubmed-meshheading:19081613-Ovalbumin,
pubmed-meshheading:19081613-T-Box Domain Proteins,
pubmed-meshheading:19081613-T-Lymphocytes,
pubmed-meshheading:19081613-Th2 Cells
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pubmed:year |
2009
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pubmed:articleTitle |
Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma.
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pubmed:affiliation |
Department of Internal Medicine, Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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