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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0025723,
umls-concept:C0040048,
umls-concept:C0185117,
umls-concept:C0205251,
umls-concept:C0332281,
umls-concept:C0741968,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C2911684,
umls-concept:C2936350
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pubmed:issue |
2
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pubmed:dateCreated |
2009-5-25
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pubmed:abstractText |
The tissue factor pathway inhibitor-2 (TFPI-2) is a Kunitz-type serine-protease inhibitor which is expressed in atherosclerotic plaques. Epigenetic regulation of the TFPI-2 gene, through methylation of CpG islands, has been advocated in cancer. We hypothesized that TFPI-2 gene methylation could regulate TFPI-2 expression in atherosclerosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1879-1484
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pubmed:author |
pubmed-author:AzzaouiRichardR,
pubmed-author:BreyneJokeJ,
pubmed-author:ChatelainNicolasN,
pubmed-author:CorseauxDelphineD,
pubmed-author:DelestreMarianneM,
pubmed-author:JeanpierreEmmanuelleE,
pubmed-author:JudeBrigitteB,
pubmed-author:JuthierFrancisF,
pubmed-author:QuesnelBrunoB,
pubmed-author:StaelsBartB,
pubmed-author:SusenSophieS,
pubmed-author:TorpierGérardG,
pubmed-author:Van BelleEricE,
pubmed-author:ZawadzkiChristopheC
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pubmed:issnType |
Electronic
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pubmed:volume |
204
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e4-14
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pubmed:meshHeading |
pubmed-meshheading:19081094-Adult,
pubmed-meshheading:19081094-Aged,
pubmed-meshheading:19081094-Aged, 80 and over,
pubmed-meshheading:19081094-Base Sequence,
pubmed-meshheading:19081094-Carotid Arteries,
pubmed-meshheading:19081094-Carotid Artery Diseases,
pubmed-meshheading:19081094-Case-Control Studies,
pubmed-meshheading:19081094-CpG Islands,
pubmed-meshheading:19081094-DNA Methylation,
pubmed-meshheading:19081094-Down-Regulation,
pubmed-meshheading:19081094-Endarterectomy, Carotid,
pubmed-meshheading:19081094-Female,
pubmed-meshheading:19081094-Genotype,
pubmed-meshheading:19081094-Glycoproteins,
pubmed-meshheading:19081094-Humans,
pubmed-meshheading:19081094-Male,
pubmed-meshheading:19081094-Middle Aged,
pubmed-meshheading:19081094-Molecular Sequence Data,
pubmed-meshheading:19081094-Phenotype,
pubmed-meshheading:19081094-Promoter Regions, Genetic,
pubmed-meshheading:19081094-RNA, Messenger
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pubmed:year |
2009
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pubmed:articleTitle |
Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques.
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pubmed:affiliation |
Université de Lille 2, EA-2693, F-59045 Lille, France. c-zawadzki@chru-lille.fr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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