Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-9-11
pubmed:abstractText
Intravenous clonidine, an alpha-2 adrenoreceptor agonist, at 2 micrograms.kg-1 and 4 micrograms.kg-1, inhibited the activation by oral copper sulphate of the reticular groove reflex in adult sheep. The plasma concentration of xylose after oral dosing was used as an indicator of groove activation. The inhibition was prevented by prior injection of an alpha-2 antagonist, idazoxan. Indirect evidence of prolongation of intestinal transit time was found with the lower dose of clonidine. Idazoxan injected alone appeared to increase the absorption of xylose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0514-7158
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
265-70
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
The inhibition of the reticular groove reflex in sheep by clonidine.
pubmed:affiliation
Department of Veterinary Preclinical Sciences, University of Liverpool, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't