Source:http://linkedlifedata.com/resource/pubmed/id/19075482
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2008-12-16
|
| pubmed:abstractText |
This study was designed to determine whether endocardial high-frequency stimulation at the pulmonary vein (PV) antrums can localize cardiac autonomic ganglionated plexi (GP) and whether ablation at these sites can evoke a vagal response and provide a long-term benefit after PV isolation (PVI) for atrial fibrillation (AF). Radiofrequency ablation of each PV antrum was performed in 21 patients with paroxysmal AF (n = 17) or persistent (n = 4) AF. In 8 patients with paroxysmal AF, a ring electrode catheter was placed at each PV antrum. High-frequency stimulation prolonged the R-R interval in 6 of 8 patients at the left superior (LS) PV, in 3 of 8 patients at the left inferior (LI) PV, in 3 of 8 patients at the right superior (RS) PV, and in 3 of 8 patients at the right inferior (RI) PV. A decrease in sinus rate > 20% was observed in 4 of 21 patients during LS PVI, in 2 of 21 patients during RS PVI, and in 1 of 2 patients during RI PVI. Atrioventricular block or a > 5 second pause was observed in 5 of 21 patients during LS PVI. AF recurred during the follow-up period in 5 of the 16 patients (31%) who had no atrioventricular block or > 5 second pause during PVI but did not recur in 5 patients in whom atrioventricular block or a > 5 second pause developed during PVI. GP can be identified by endocardial stimulation. The AF recurrence rate is decreased when a vagal response is achieved by radiofrequency ablation.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
1349-2365
|
| pubmed:author |
pubmed-author:AshinoSonokoS,
pubmed-author:HashimotoKenichiK,
pubmed-author:HirayamaAtsushiA,
pubmed-author:KasamakiYujiY,
pubmed-author:KofuneMasayoshiM,
pubmed-author:KofuneTatsuyaT,
pubmed-author:KunimotoSatoshiS,
pubmed-author:NakaiToshikoT,
pubmed-author:OhkuboKimieK,
pubmed-author:OkumuraYasuoY,
pubmed-author:ShindoAtsushiA,
pubmed-author:SugimuraHidezouH,
pubmed-author:TakagiYasuhiroY,
pubmed-author:WatanabeIchiroI,
pubmed-author:YamadaTakeshiT
|
| pubmed:issnType |
Print
|
| pubmed:volume |
49
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
661-70
|
| pubmed:meshHeading |
pubmed-meshheading:19075482-Adult,
pubmed-meshheading:19075482-Aged,
pubmed-meshheading:19075482-Atrial Fibrillation,
pubmed-meshheading:19075482-Autonomic Pathways,
pubmed-meshheading:19075482-Catheter Ablation,
pubmed-meshheading:19075482-Electric Stimulation,
pubmed-meshheading:19075482-Female,
pubmed-meshheading:19075482-Heart,
pubmed-meshheading:19075482-Humans,
pubmed-meshheading:19075482-Male,
pubmed-meshheading:19075482-Middle Aged,
pubmed-meshheading:19075482-Pulmonary Veins,
pubmed-meshheading:19075482-Recurrence
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Combined effect of pulmonary vein isolation and ablation of cardiac autonomic nerves for atrial fibrillation.
|
| pubmed:affiliation |
Department of Cardiovascular Disease, Nihon University School of Medicine, Tokyo, Japan.
|
| pubmed:publicationType |
Journal Article
|