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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1991-9-3
|
| pubmed:abstractText |
A method combining immune capture and enzyme detection by fluorochemistry has been developed for the diagnostic assay of N-acetylgalactosamine-4-sulphatase (4-sulphatase). The procedure uses a monoclonal antibody 4-S 4.1 to immunoadsorb 4-sulphatase specifically from complex protein samples containing other sulphatases, and 4-methylumbelliferyl sulphate to detect captured 4-sulphatase. The assay provides an accurate and simple method for the diagnosis of Maroteaux-Lamy syndrome (Mucopolysaccharidosis type VI).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0141-8955
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
5-12
|
| pubmed:dateRevised |
2007-3-21
|
| pubmed:meshHeading |
pubmed-meshheading:1907337-Antibodies, Monoclonal,
pubmed-meshheading:1907337-Chondro-4-Sulfatase,
pubmed-meshheading:1907337-Humans,
pubmed-meshheading:1907337-Hymecromone,
pubmed-meshheading:1907337-Immunoenzyme Techniques,
pubmed-meshheading:1907337-Immunosorbent Techniques,
pubmed-meshheading:1907337-Mucopolysaccharidosis IV,
pubmed-meshheading:1907337-Spectrometry, Fluorescence
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
A specific fluorogenic assay for N-acetylgalactosamine-4-sulphatase activity using immunoadsorption.
|
| pubmed:affiliation |
Department of Chemical Pathology, Adelaide Medical Centre for Women and Children, Australia.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|