Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-2-16
pubmed:abstractText
Multiple parasite infections are widespread in the developing world and understanding their geographical distribution is important for spatial targeting of differing intervention packages. We investigated the spatial epidemiology of mono- and co-infection with helminth parasites in East Africa and developed a geostatistical model to predict infection risk. The data used for the analysis were taken from standardised school surveys of Schistosoma mansoni and hookworm (Ancylostoma duodenale/Necator americanus) carried out between 1999 and 2005 in East Africa. Prevalence of mono- and co-infection was modelled using satellite-derived environmental and demographic variables as potential predictors. A Bayesian multi-nominal geostatistical model was developed for each infection category for producing maps of predicted co-infection risk. We show that heterogeneities in co-infection with S. mansoni and hookworm are influenced primarily by the distribution of S. mansoni, rather than the distribution of hookworm, and that temperature, elevation and distance to large water bodies are reliable predictors of the spatial large-scale distribution of co-infection. On the basis of these results, we developed a validated geostatistical model of the distribution of co-infection at a scale that is relevant for planning regional disease control efforts that simultaneously target multiple parasite species.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-10997209, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-11442193, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-11454244, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-1304710, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-14700188, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-14996367, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-15463638, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-15608702, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-15635963, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-15737065, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-15764695, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16038401, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16306991, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16357113, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16371253, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16553932, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16632601, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16647967, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16824566, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16917658, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16953953, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-16989681, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17055547, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17172362, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17540894, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17556602, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17716433, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17804846, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-17913894, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-18182496, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-18371242, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-18621051, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-18686239, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-18686258, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-1887492, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-3729596, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-3904343, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-5974753, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-5976975, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-8988928, http://linkedlifedata.com/resource/pubmed/commentcorrection/19073189-8990210
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1879-0135
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
591-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Spatial heterogeneity of parasite co-infection: Determinants and geostatistical prediction at regional scales.
pubmed:affiliation
Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. simon.brooker@lshtm.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't