Source:http://linkedlifedata.com/resource/pubmed/id/19071122
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2008-12-29
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pubmed:abstractText |
The Woronin body, a septal pore-associated organelle specific to filamentous ascomycetes, is crucial for preventing cytoplasmic bleeding after hyphal injury. In this study, we show that T1hex-1 transcript and a variant splicing T2hex-1 transcript are up-regulated at alkaline pH. We also show that both hex-1 transcripts are overexpressed in the preg(c), nuc-1(RIP), and pacC(ko) mutant strains of Neurospora crassa grown under conditions of phosphate shortage at alkaline pH, suggesting that hex-1 transcription may be coregulated by these genes. In addition, we present evidence that N. crassa PacC also has metabolic functions at acidic pH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1873-3468
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
583
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
180-4
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pubmed:meshHeading |
pubmed-meshheading:19071122-Alternative Splicing,
pubmed-meshheading:19071122-Fungal Proteins,
pubmed-meshheading:19071122-Gene Expression Regulation, Fungal,
pubmed-meshheading:19071122-Hydrogen-Ion Concentration,
pubmed-meshheading:19071122-Neurospora crassa,
pubmed-meshheading:19071122-Organelles,
pubmed-meshheading:19071122-Phosphates,
pubmed-meshheading:19071122-Up-Regulation
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pubmed:year |
2009
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pubmed:articleTitle |
A splice variant of the Neurospora crassa hex-1 transcript, which encodes the major protein of the Woronin body, is modulated by extracellular phosphate and pH changes.
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pubmed:affiliation |
Departamento de Genética, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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