Linked Life Data

19067761

Source:http://linkedlifedata.com/resource/pubmed/id/19067761

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-12-10
pubmed:abstractText
The multifactorial process of carcinogenesis involves mutations in oncogenes, or tumor suppressor genes, as well as the influence of environmental etiological factors. Common DNA polymorphisms in low penetrance genes have emerged as genetic factors that seem to modulate an individual's susceptibility to malignancy. Genetic studies, which lead to a true association, are expected to increase understanding of the pathogenesis of each malignancy and to be a powerful tool for prevention and prognosis in the future. Here, we review the findings of genetic association studies of gene polymorphisms in gynecologic cancer with special reference to glutathione-S-transferase, FAS/CD95 and p53 genes including our recent research results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0914-7470
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
95-104
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Germline polymorphism of cancer susceptibility genes in gynecologic cancer.
pubmed:affiliation
Cytopathology and Gynecology, Osaka Cancer Prevention and Detection Center, Osaka, Japan. mueda@gan-osaka.or.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't