Source:http://linkedlifedata.com/resource/pubmed/id/19067742
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-1-12
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pubmed:abstractText |
The characteristic chromosomal translocation t(9;22)(q34;q11) in chronic myeloid leukaemia (CML) mainly results in the two different BCR/ABL fusion transcripts b2a2 or b3a2. Both transcript variants can occur simultaneously due to alternative splicing of the b3a2 transcript. Conflicting results have been reported on the influence of the transcripts on haematological findings at diagnosis and the course of the disease in adults while data concerning these topics on childhood CML are still missing. This paper reports on a correlation of BCR/ABL transcript variants with patients' characteristics in childhood CML.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1600-0609
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
112-8
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pubmed:meshHeading |
pubmed-meshheading:19067742-Adolescent,
pubmed-meshheading:19067742-Base Sequence,
pubmed-meshheading:19067742-Child,
pubmed-meshheading:19067742-Child, Preschool,
pubmed-meshheading:19067742-Chromosome Banding,
pubmed-meshheading:19067742-Cohort Studies,
pubmed-meshheading:19067742-DNA Primers,
pubmed-meshheading:19067742-Female,
pubmed-meshheading:19067742-Genes, abl,
pubmed-meshheading:19067742-Humans,
pubmed-meshheading:19067742-Infant,
pubmed-meshheading:19067742-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:19067742-Male,
pubmed-meshheading:19067742-RNA, Messenger,
pubmed-meshheading:19067742-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Correlation of BCR/ABL transcript variants with patients' characteristics in childhood chronic myeloid leukaemia.
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pubmed:affiliation |
Division of Paediatric Haematology and Oncology, University Hospital Carl Gustav Carus, Technical University at Dresden, Dresden, Germany.
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pubmed:publicationType |
Journal Article
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