|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2009-2-2
|
|
pubmed:abstractText |
Toll-like receptor 4 (TLR4) is the major endotoxin signalling receptor of the innate immune system and is required for efficient recognition of bacterial infections. Here, we analysed a possible association between the TLR4 variant Asp299Gly and disease outcome in children with invasive meningococcal disease.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1651-2227
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
98
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
548-52
|
|
pubmed:meshHeading |
pubmed-meshheading:19067670-Adolescent,
pubmed-meshheading:19067670-Amino Acid Substitution,
pubmed-meshheading:19067670-Child,
pubmed-meshheading:19067670-Child, Preschool,
pubmed-meshheading:19067670-Europe,
pubmed-meshheading:19067670-Female,
pubmed-meshheading:19067670-Gene Frequency,
pubmed-meshheading:19067670-Genotype,
pubmed-meshheading:19067670-Humans,
pubmed-meshheading:19067670-Infant,
pubmed-meshheading:19067670-Male,
pubmed-meshheading:19067670-Meningococcal Infections,
pubmed-meshheading:19067670-Toll-Like Receptor 4,
pubmed-meshheading:19067670-Young Adult
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
A toll-like receptor 4 variant is associated with fatal outcome in children with invasive meningococcal disease.
|
|
pubmed:affiliation |
Children's Hospital, University of Mainz, Mainz, Germany. jorg.faber@childrens.harvard.edu
|
|
pubmed:publicationType |
Journal Article,
Multicenter Study
|
