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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-21
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pubmed:abstractText |
Endothelial progenitor cells (EPCs) in bone marrow (BM) and peripheral blood (PB) contribute to tissue repair in various pathological conditions via the formation of new blood vessels. Previous studies indicate that diabetic patients have reduced EPC number and deregulated EPC function, although the regenerative properties of EPCs in diabetes are unknown. We wish to characterize and compare EPCs from pre-diabetic and diabetic non-obese diabetic (NOD) mice, a model of type 1 diabetes (T1D), in order to delineate the role of these cells in the pathogenesis of autoimmune diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1520-7560
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 John Wiley & Sons, Ltd.
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-93
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pubmed:meshHeading |
pubmed-meshheading:19065604-Animals,
pubmed-meshheading:19065604-Bone Marrow Cells,
pubmed-meshheading:19065604-Cell Count,
pubmed-meshheading:19065604-Diabetes Mellitus, Type 1,
pubmed-meshheading:19065604-Endothelial Cells,
pubmed-meshheading:19065604-Female,
pubmed-meshheading:19065604-Femur,
pubmed-meshheading:19065604-Flow Cytometry,
pubmed-meshheading:19065604-Ilium,
pubmed-meshheading:19065604-Male,
pubmed-meshheading:19065604-Mice,
pubmed-meshheading:19065604-Mice, Inbred BALB C,
pubmed-meshheading:19065604-Mice, Inbred NOD,
pubmed-meshheading:19065604-Neovascularization, Physiologic,
pubmed-meshheading:19065604-Prediabetic State,
pubmed-meshheading:19065604-Stem Cells,
pubmed-meshheading:19065604-Tibia,
pubmed-meshheading:19065604-Tissue Therapy
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pubmed:year |
2009
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pubmed:articleTitle |
Characterization of endothelial progenitor cells in the NOD mouse as a source for cell therapies.
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pubmed:affiliation |
Queen Mary's School of Medicine and Dentistry of London, Centre for Diabetes and Metabolic Medicine, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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