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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-12-9
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pubmed:abstractText |
Several placebo-controlled clinical studies suggest that products containing isoleucyl-prolyl-proline and valyl-prolyl-proline are able to lower blood pressure without adverse effects. The most efficient way of producing high concentrations of these lactotripeptides (LTPs) is enzymatic hydrolysis of dairy protein (casein) with the use of a mixture of several enzymes derived from the nongenetically modified organism Aspergillus oryzae, including proteases and peptidases. To date, no large studies of the blood pressure-lowering properties of enzymatically produced LTP (ELTP) powder in European populations have been published.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1938-3207
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1697-702
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pubmed:dateRevised |
2009-5-15
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pubmed:meshHeading |
pubmed-meshheading:19064533-Adult,
pubmed-meshheading:19064533-Aged,
pubmed-meshheading:19064533-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:19064533-Blood Pressure,
pubmed-meshheading:19064533-Cultured Milk Products,
pubmed-meshheading:19064533-Diastole,
pubmed-meshheading:19064533-Double-Blind Method,
pubmed-meshheading:19064533-Female,
pubmed-meshheading:19064533-Humans,
pubmed-meshheading:19064533-Hypertension,
pubmed-meshheading:19064533-Male,
pubmed-meshheading:19064533-Middle Aged,
pubmed-meshheading:19064533-Netherlands,
pubmed-meshheading:19064533-Oligopeptides,
pubmed-meshheading:19064533-Peptides,
pubmed-meshheading:19064533-Systole,
pubmed-meshheading:19064533-Treatment Failure,
pubmed-meshheading:19064533-Urinalysis,
pubmed-meshheading:19064533-Yogurt
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pubmed:year |
2008
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pubmed:articleTitle |
Enzymatically hydrolyzed lactotripeptides do not lower blood pressure in mildly hypertensive subjects.
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pubmed:affiliation |
Unilever Food & Health Research Institute, Vlaardingen, Netherlands.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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