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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-3-2
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pubmed:abstractText |
Cerebral cavernous malformations (CCMs) are the most common vascular malformation of the central nervous system and involve dysregulated angiogenesis. However, the underlying mechanism of this disease is poorly understood. Phosphatase and tensin homolog (PTEN) plays a crucial role in regulating angiogenesis. The authors attempted to determine whether PTEN is involved in the pathological angiogenesis of CCM.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-3085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
530-9
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pubmed:meshHeading |
pubmed-meshheading:19061355-Adult,
pubmed-meshheading:19061355-Blotting, Western,
pubmed-meshheading:19061355-Cells, Cultured,
pubmed-meshheading:19061355-Endothelial Cells,
pubmed-meshheading:19061355-Female,
pubmed-meshheading:19061355-Humans,
pubmed-meshheading:19061355-Immunohistochemistry,
pubmed-meshheading:19061355-Intracranial Arteriovenous Malformations,
pubmed-meshheading:19061355-Male,
pubmed-meshheading:19061355-Middle Aged,
pubmed-meshheading:19061355-Neovascularization, Pathologic,
pubmed-meshheading:19061355-PTEN Phosphohydrolase
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pubmed:year |
2009
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pubmed:articleTitle |
Phosphatase and tensin homolog in cerebral cavernous malformation: a potential role in pathological angiogenesis.
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pubmed:affiliation |
Departments of Neurosurgery, University of Marburg, Marburg, Germany. yuan.zhu@uk-essen.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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