rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0022702,
umls-concept:C0023449,
umls-concept:C0032952,
umls-concept:C0034809,
umls-concept:C0087111,
umls-concept:C0185117,
umls-concept:C0205419,
umls-concept:C0231335,
umls-concept:C1515655,
umls-concept:C2911684
|
pubmed:issue |
4
|
pubmed:dateCreated |
2009-2-16
|
pubmed:abstractText |
The in vivo glucocorticoid response in childhood acute lymphoblastic leukaemia (ALL) correlates with the response to multi-agent chemotherapy. However, it is still unclear, whether the expression levels of glucocorticoid receptor (GR) splice variants facilitate the escape from glucocorticoid-induced apoptosis and hence contribute to glucocorticoid resistance.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1545-5017
|
pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2008 Wiley-Liss, Inc.
|
pubmed:issnType |
Electronic
|
pubmed:volume |
52
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
459-63
|
pubmed:meshHeading |
pubmed-meshheading:19061214-Antineoplastic Agents, Hormonal,
pubmed-meshheading:19061214-Case-Control Studies,
pubmed-meshheading:19061214-Child,
pubmed-meshheading:19061214-Child, Preschool,
pubmed-meshheading:19061214-Female,
pubmed-meshheading:19061214-Gene Expression,
pubmed-meshheading:19061214-Humans,
pubmed-meshheading:19061214-Infant,
pubmed-meshheading:19061214-Male,
pubmed-meshheading:19061214-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:19061214-Prednisone,
pubmed-meshheading:19061214-Protein Isoforms,
pubmed-meshheading:19061214-Receptors, Glucocorticoid,
pubmed-meshheading:19061214-Reverse Transcriptase Polymerase Chain Reaction
|
pubmed:year |
2009
|
pubmed:articleTitle |
Kinetics of the in vivo expression of glucocorticoid receptor splice variants during prednisone treatment in childhood acute lymphoblastic leukaemia.
|
pubmed:affiliation |
Department of Paediatrics and Adolescent Medicine, Division of Paediatric Haematology and Oncology, University of Freiburg, Mathildenstrasse, Freiburg, Germany. melchior.lauten@uniklinik-freiburg.de
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|