Source:http://linkedlifedata.com/resource/pubmed/id/19054641
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2010-2-1
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| pubmed:abstractText |
The aim of the present study was to assess occupationally induced chromosomal damage in hospital workers exposed to low levels of ionizing radiation. Thirty-two interventional cardiologists, 36 nuclear medicine physicians and 33 conventional radiologists were included in this study, along with 35 healthy age- and sex-matched individuals as the control group. We used conventional metaphase chromosome aberration (CA) analysis, cytokinesis-block micronucleus (MN) assay as important biological indicators of ionizing radiation exposure. Occupational dosimetry records were collected over the last year (ranged from 0.25 to 48mSv) and their whole life exposure (ranged from 1.5 to 147mSv). The results showed significantly higher frequencies of dicentric and acentric CAs (p<0.001) and MN (p<0.01) in all exposed groups than in the controls. Taking all the confounding factors into account, no obvious trend of increased chromosomal damages as a function of either duration of employment, exposed dose, sex or age was observed. Interventional cardiologists had the highest rates of CA and MN frequencies between the worker groups, though the differences were not significant. These results indicate that long term exposure to low dose ionizing radiation could result in DNA damage. Hence, the personnel who work in the hospitals should carefully apply the radiation protection procedures.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jan
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| pubmed:issn |
1872-7727
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
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| pubmed:issnType |
Electronic
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| pubmed:volume |
73
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
191-5
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| pubmed:meshHeading |
pubmed-meshheading:19054641-Adult,
pubmed-meshheading:19054641-Biological Assay,
pubmed-meshheading:19054641-Cytogenetic Analysis,
pubmed-meshheading:19054641-Female,
pubmed-meshheading:19054641-Humans,
pubmed-meshheading:19054641-Iran,
pubmed-meshheading:19054641-Male,
pubmed-meshheading:19054641-Medical Staff, Hospital,
pubmed-meshheading:19054641-Middle Aged,
pubmed-meshheading:19054641-Occupational Exposure,
pubmed-meshheading:19054641-Radiation, Ionizing,
pubmed-meshheading:19054641-Relative Biological Effectiveness,
pubmed-meshheading:19054641-Whole-Body Counting
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| pubmed:year |
2010
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| pubmed:articleTitle |
A cytogenetic approach to the effects of low levels of ionizing radiations on occupationally exposed individuals.
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| pubmed:affiliation |
National Radiation Protection Department, Iranian Nuclear Regulatory Authority, Nuclear Science and Research Institute-Agriculture, Medicine & Industry Research School, Tehran, Iran. fzakeri@aeoi.org.ir
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| pubmed:publicationType |
Journal Article
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