Linked Life Data

19052983

Source:http://linkedlifedata.com/resource/pubmed/id/19052983

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2008-12-4
pubmed:abstractText
A case-only study was conducted in 123 patients with sporadic acute leukemia (AL). The locations of electric transformers and power lines were noted in each area, and their distances from the houses of the study patients were measured. The intensities of magnetic fields (B) were measured in 66 cases. Unconditional logistic regression analysis was performed adjusting for age, gender, parental education and occupation, indoor and outdoor pesticides use, presence of television sets, refrigerators and microwave ovens in children's rooms and the presence of chemical factories or telecommunication transmitters within 500 m of the houses. The results of the gene-environment analyses revealed that an interaction existed between the XRCC1 Ex9+16 A allele and the presence of electric transformers and power lines within 100 m (Mean B=0.14 microTeslas, microT) of the houses (interaction odds ratio, COR=4.31, 95%CI: 1.54-12.08). The COR for the interaction of XRCC1 Ex9+16A and the presence of these installations within 50 m (Mean B=0.18 microT) of the houses was 4.39 (95%CI: 1.42-13.54). Our results suggest a possible association between electric transformers and power lines and the XRCC1 Ex9+16A allele in patients with childhood AL.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1029-2403
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2344-50
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Case-only study of interactions between DNA repair genes (hMLH1, APEX1, MGMT, XRCC1 and XPD) and low-frequency electromagnetic fields in childhood acute leukemia.
pubmed:affiliation
Shanghai XinHua Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai Institute for Pediatric Research, Shanghai Key Laboratory of Children's Environmental Health, Shanghai, China.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't