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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-1-12
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pubmed:abstractText |
A prior study demonstrated that addition of continuous daily erlotinib fails to improve response rate or survival in non-small-cell lung cancer (NSCLC) patients treated with carboplatin and paclitaxel. However, preclinical data support the hypothesis that intermittent administration of erlotinib before or after chemotherapy may improve efficacy. We tested this hypothesis in patients with advanced NSCLC.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-10815932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-10999768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-11156248,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-11585753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-12748244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-12775734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-14570950,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-14990632,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-14990633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15020612,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15118073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15118125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15169807,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15310767,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15329413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15345335,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-15756024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-16014882,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-16043829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-16878326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-16896930,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-17167137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-17442998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-17925489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19047285-18186959
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:AzzoliChristopher GCG,
pubmed-author:BrahmerJulie RJR,
pubmed-author:FogleMargaretM,
pubmed-author:GinsbergMichelleM,
pubmed-author:KrisMark GMG,
pubmed-author:MillerVincent AVA,
pubmed-author:MiltonDaniel TDT,
pubmed-author:RielyGregory JGJ,
pubmed-author:RizviNaiyer ANA,
pubmed-author:RosenNealN,
pubmed-author:RudinCharles MCM,
pubmed-author:SenturkEmirE,
pubmed-author:SeshanVenkatraman EVE,
pubmed-author:SirotnakFrancis MFM,
pubmed-author:SolitDavid BDB
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pubmed:issnType |
Electronic
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pubmed:day |
10
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
264-70
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pubmed:dateRevised |
2010-9-23
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pubmed:meshHeading |
pubmed-meshheading:19047285-Adult,
pubmed-meshheading:19047285-Aged,
pubmed-meshheading:19047285-Aged, 80 and over,
pubmed-meshheading:19047285-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19047285-Carboplatin,
pubmed-meshheading:19047285-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:19047285-Drug Administration Schedule,
pubmed-meshheading:19047285-Female,
pubmed-meshheading:19047285-Genes, ras,
pubmed-meshheading:19047285-Humans,
pubmed-meshheading:19047285-Lung Neoplasms,
pubmed-meshheading:19047285-Male,
pubmed-meshheading:19047285-Middle Aged,
pubmed-meshheading:19047285-Neoplasm Staging,
pubmed-meshheading:19047285-Paclitaxel,
pubmed-meshheading:19047285-Quinazolines,
pubmed-meshheading:19047285-Receptor, Epidermal Growth Factor,
pubmed-meshheading:19047285-Smoking,
pubmed-meshheading:19047285-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Randomized phase II study of pulse erlotinib before or after carboplatin and paclitaxel in current or former smokers with advanced non-small-cell lung cancer.
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pubmed:affiliation |
Thoracic Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10022, USA. rielyg@mskcc.org
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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