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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-2-3
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pubmed:abstractText |
Vasculogenic mimicry (VM) is a tumor angiogenesis process in which highly aggressive melanoma cells form patterned, tubular networks in an in vitro, three-dimensional culture that mimics vasculogenic networks formed by endothelial cells. These cells also express endothelial cell-associated genes such as vascular endothelial-cadherin (VE-cadherin) and are correlated with poor clinical prognosis in patients. However, the molecular underpinnings of this phenomenon remain elusive.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1435-702X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
247
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
411-9
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pubmed:meshHeading |
pubmed-meshheading:19043732-Antigens, CD,
pubmed-meshheading:19043732-Blotting, Western,
pubmed-meshheading:19043732-Cadherins,
pubmed-meshheading:19043732-Cell Movement,
pubmed-meshheading:19043732-Endothelium, Vascular,
pubmed-meshheading:19043732-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19043732-Gene Silencing,
pubmed-meshheading:19043732-Humans,
pubmed-meshheading:19043732-Inhibitor of Differentiation Protein 2,
pubmed-meshheading:19043732-Melanoma,
pubmed-meshheading:19043732-Microscopy, Electron, Scanning,
pubmed-meshheading:19043732-Microscopy, Phase-Contrast,
pubmed-meshheading:19043732-Molecular Mimicry,
pubmed-meshheading:19043732-Neovascularization, Pathologic,
pubmed-meshheading:19043732-RNA, Small Interfering,
pubmed-meshheading:19043732-RNA Interference,
pubmed-meshheading:19043732-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19043732-Tumor Cells, Cultured,
pubmed-meshheading:19043732-Uveal Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
Molecular regulation of vasculogenic mimicry in human uveal melanoma cells: role of helix-loop-helix Id2 (inhibitor of DNA binding 2).
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pubmed:affiliation |
Beijing Institute of Ophthalmology, Beijing TongRen hospital, Capital Medical University, 17 Hougou Lane, Chong Wen Men, Beijing, 100005, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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