Source:http://linkedlifedata.com/resource/pubmed/id/19042922
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2009-7-7
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pubmed:abstractText |
Sequence variation within the COL5A1 and TNC genes are known to associate with Achilles tendinopathy. The primary aim of this case-control genetic association study was to investigate whether variants within the matrix metalloproteinase 3 (MMP3) gene also contributed to both Achilles tendinopathy and Achilles tendon rupture in a Caucasian population. A secondary aim was to establish whether variants within the MMP3 gene interacted with the COL5A1 rs12722 variant to raise risk of these pathologies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1473-0480
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
514-20
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pubmed:meshHeading |
pubmed-meshheading:19042922-Achilles Tendon,
pubmed-meshheading:19042922-Adult,
pubmed-meshheading:19042922-Case-Control Studies,
pubmed-meshheading:19042922-Collagen Type V,
pubmed-meshheading:19042922-Epistasis, Genetic,
pubmed-meshheading:19042922-Female,
pubmed-meshheading:19042922-Gene Frequency,
pubmed-meshheading:19042922-Genotype,
pubmed-meshheading:19042922-Humans,
pubmed-meshheading:19042922-Linkage Disequilibrium,
pubmed-meshheading:19042922-Male,
pubmed-meshheading:19042922-Matrix Metalloproteinase 3,
pubmed-meshheading:19042922-Polymorphism, Single Nucleotide,
pubmed-meshheading:19042922-Tendinopathy
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pubmed:year |
2009
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pubmed:articleTitle |
Variants within the MMP3 gene are associated with Achilles tendinopathy: possible interaction with the COL5A1 gene.
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pubmed:affiliation |
Division of Health and Life Sciences, University of Northampton, Park Campus, Boughton Green Road, Northampton NN2 7AL, UK. Stuart.Raleigh@northampton.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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