19041150

Source:http://linkedlifedata.com/resource/pubmed/id/19041150

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0019647, umls-concept:C0025723, umls-concept:C0086418, umls-concept:C0205349, umls-concept:C0332281, umls-concept:C0345904, umls-concept:C1367731, umls-concept:C1879547
pubmed:issue	2
pubmed:dateCreated	2009-1-16
pubmed:abstractText	Aberrant c-Jun N-terminal kinase (JNK) activation has been linked to hepatocellular carcinoma (HCC) in mouse models. It remains unclear whether JNK activation plays an important role in human HCC and, if so, how JNK signaling contributes to the initiation or progression of HCC.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/5R01CA116697, http://linkedlifedata.com/resource/pubmed/grant/5R01CA119028
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8503886
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/EZH2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Histones, http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 8, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0168-8278
pubmed:author	pubmed-author:BeezholdKevin JKJ, pubmed-author:BhatiaDeepakD, pubmed-author:CastranovaVinceV, pubmed-author:ChangQingshanQ, pubmed-author:ChenFeiF, pubmed-author:ChenJianguoJ, pubmed-author:ShiXianglinX, pubmed-author:ZhangYadongY, pubmed-author:ZhaoHongwenH
pubmed:issnType	Print
pubmed:volume	50
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	323-33
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:19041150-Adult, pubmed-meshheading:19041150-Aged, pubmed-meshheading:19041150-Carcinoma, Hepatocellular, pubmed-meshheading:19041150-DNA-Binding Proteins, pubmed-meshheading:19041150-Enzyme Activation, pubmed-meshheading:19041150-Female, pubmed-meshheading:19041150-Gene Expression Profiling, pubmed-meshheading:19041150-Gene Expression Regulation, pubmed-meshheading:19041150-Histones, pubmed-meshheading:19041150-Humans, pubmed-meshheading:19041150-Liver, pubmed-meshheading:19041150-Liver Neoplasms, pubmed-meshheading:19041150-Male, pubmed-meshheading:19041150-Methylation, pubmed-meshheading:19041150-Middle Aged, pubmed-meshheading:19041150-Mitogen-Activated Protein Kinase 8, pubmed-meshheading:19041150-Signal Transduction, pubmed-meshheading:19041150-Transcription Factors
pubmed:year	2009
pubmed:articleTitle	Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer.
pubmed:affiliation	Graduate Center for Toxicology, University of Kentucky, Lexington, KY 40536, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural