Source:http://linkedlifedata.com/resource/pubmed/id/19040338
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
18
|
pubmed:dateCreated |
2008-12-1
|
pubmed:abstractText |
Neuronal hyperexcitability and excessive production of free radicals have been implicated in the pathogenesis of a considerable range of neurological disorders, including epilepsy. The high rate of oxidative metabolism, coupled with the low antioxidant defenses and the richness in polyunsaturated fatty acids, makes the brain highly vulnerable to free radical damage. The increased susceptibility of the brain to oxidative damage highlights the importance of understanding the role of oxidative stress in the pathophysiology of seizures.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
1744-7666
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3169-77
|
pubmed:meshHeading |
pubmed-meshheading:19040338-Animals,
pubmed-meshheading:19040338-Anticonvulsants,
pubmed-meshheading:19040338-Antioxidants,
pubmed-meshheading:19040338-Brain,
pubmed-meshheading:19040338-Humans,
pubmed-meshheading:19040338-Mitochondrial Diseases,
pubmed-meshheading:19040338-Nervous System Diseases,
pubmed-meshheading:19040338-Oxidants,
pubmed-meshheading:19040338-Oxidative Stress,
pubmed-meshheading:19040338-Seizures
|
pubmed:year |
2008
|
pubmed:articleTitle |
Seizures, antiepileptics, antioxidants and oxidative stress: an insight for researchers.
|
pubmed:affiliation |
Research Scientist (MACR) Ranbaxy Research Laboratories, Udyog Vihar Industrial Area, 20, Sector-18, IFFCO Road, Gurgaon 122015, Haryana, India.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|