Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-7-2
pubmed:abstractText
We studied the susceptibilities of 77 strains of Neisseria gonorrhoeae to four antibiotics: cefpodoxime, ceftriaxone, penicillin, and tetracycline. All strains were susceptible to ceftriaxone. Cefpodoxime MICs (range, 0.001 to 0.125 micrograms/ml) were parallel to and approximately four times those of ceftriaxone, and all strains will probably be considered susceptible to cefpodoxime. Disk diffusion zone diameters for cefpodoxime ranged from 35 to 57 mm. Of the strains, 32% were penicillin resistant and 51% were tetracycline resistant (MIC, greater than or equal to 2 micrograms/ml). Susceptibility measurements were consistent for disk diffusion zone diameter and MIC, with an overall agreement of 215 of 225 (96%) for ceftriaxone, penicillin, and tetracycline combined. On the basis of these in vitro data, cefpodoxime should be evaluated in the treatment of gonorrhea.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2109583, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2113796, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2351624, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2393268, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2497703, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2531756, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-2764526, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-3102635, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-3128961, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-3245701, http://linkedlifedata.com/resource/pubmed/commentcorrection/1903910-3934128
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0066-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
497-9
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Susceptibility of Neisseria gonorrhoeae to cefpodoxime: determination of MICs and disk diffusion zone diameters.
pubmed:affiliation
Department of Internal Medicine, Temple University Health Sciences Center, Philadelphia, Pennsylvania 19140.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't