Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-3-3
pubmed:abstractText
Percutaneous radiofrequency ablation is the treatment of choice for osteoid osteoma of the appendicular skeleton. However, difficulties in localizing the lesion in the spine and its proximity to neural elements have yet to make it the prevalent treatment for spine. This study assesses the safety and effectiveness of two percutaneous techniques for ablating osteoid osteoma of the spine. Seven patients were treated between 1998 and 2005. Four patients underwent percutaneous radiofrequency coagulation. The lesions were located at the articular processes of L3 and L4, the lamina of L3 and in the head of the 11th rib. Three patients with lesions in close proximity to neural structures (pedicle of T9, the posterolateral inferior aspect of L3 vertebral body and the inferior articular process of C5) were subjected to percutaneous core excision. Mean follow-up was 4.2 +/- 1.6 years. Three out of four patients who underwent radiofrequency ablation had an immediate and sustained response. One patient with a lesion in the head of the rib failed to respond. The three patients in the group of pecutaneous core excisional biopsy demonstrated immediate relief of pain. However, one patient experienced relapse of symptoms 6 months after transpedicular core excision. CT scan suggested partial targeting of the lesion that corroborated with histologic examination revealing only reactive tissue. Subsequent percutaneous core excision was successful. Therefore, the overall success rate was 85.7%. Mean VAS improved dramatically from 9 +/- 1 to 2 +/- 1 after surgery (P < 0.05). No neurological or other complications were encountered. This study indicates that radiofrequency ablation of spinal osteoid osteomas is safe and reasonably effective when an intact cortical shell separates the nidus from the neural elements. Percutaneous core excision can obviate the risk of thermal damage for lesions located in close proximity to the neural elements. Effectiveness of treatment can also be evaluated by CT scan and histological examination. Difficulties in targeting the nidus can lead to treatment failure. The minimal morbidity and the effectiveness of these minimally invasive procedures make them a valid alternative in the treatment of spinal osteoid osteoma.
pubmed:commentsCorrections
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pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1432-0932
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
345-51
pubmed:dateRevised
2010-9-23
pubmed:meshHeading
pubmed-meshheading:19031087-Adolescent, pubmed-meshheading:19031087-Adult, pubmed-meshheading:19031087-Age Distribution, pubmed-meshheading:19031087-Catheter Ablation, pubmed-meshheading:19031087-Disease Progression, pubmed-meshheading:19031087-Female, pubmed-meshheading:19031087-Humans, pubmed-meshheading:19031087-Laminectomy, pubmed-meshheading:19031087-Male, pubmed-meshheading:19031087-Neurosurgical Procedures, pubmed-meshheading:19031087-Osteoma, Osteoid, pubmed-meshheading:19031087-Ribs, pubmed-meshheading:19031087-Scoliosis, pubmed-meshheading:19031087-Spinal Neoplasms, pubmed-meshheading:19031087-Spine, pubmed-meshheading:19031087-Surgical Procedures, Minimally Invasive, pubmed-meshheading:19031087-Tomography, X-Ray Computed, pubmed-meshheading:19031087-Treatment Outcome, pubmed-meshheading:19031087-Young Adult
pubmed:year
2009
pubmed:articleTitle
Percutaneous core excision and radiofrequency thermo-coagulation for the ablation of osteoid osteoma of the spine.
pubmed:affiliation
Department of Orthopaedics and Traumatology, University of Crete, Heraklion, Crete, Greece. ahadjipa@med.uoc.gr
pubmed:publicationType
Journal Article