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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-11-25
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pubmed:abstractText |
Impaired renal microcirculation has been suggested as a factor contributing to the development of renal dysfunction in sepsis. This study was conducted to elucidate the role of endothelin-1 (ET-1)in mediating reductions in renal microcirculatory blood flow during endotoxemic shock.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1399-6576
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1385-93
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pubmed:meshHeading |
pubmed-meshheading:19025532-Aldosterone,
pubmed-meshheading:19025532-Angiotensin II,
pubmed-meshheading:19025532-Animals,
pubmed-meshheading:19025532-Disease Models, Animal,
pubmed-meshheading:19025532-Endotoxemia,
pubmed-meshheading:19025532-Female,
pubmed-meshheading:19025532-Hemodynamics,
pubmed-meshheading:19025532-Interleukins,
pubmed-meshheading:19025532-Kidney,
pubmed-meshheading:19025532-Microcirculation,
pubmed-meshheading:19025532-Osmolar Concentration,
pubmed-meshheading:19025532-Pyridines,
pubmed-meshheading:19025532-Random Allocation,
pubmed-meshheading:19025532-Receptors, Endothelin,
pubmed-meshheading:19025532-Swine,
pubmed-meshheading:19025532-Tetrazoles,
pubmed-meshheading:19025532-Treatment Outcome,
pubmed-meshheading:19025532-Tumor Necrosis Factor-alpha,
pubmed-meshheading:19025532-Vasodilator Agents
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pubmed:year |
2008
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pubmed:articleTitle |
The endothelin receptor antagonist tezosentan improves renal microcirculation in a porcine model of endotoxemic shock.
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pubmed:affiliation |
Department of Anaesthesia and Intensive Care, Karolinska University Hospital, Stockholm, Sweden. johan.fenhammar@karolinska.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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