Linked Life Data

19023589

Source:http://linkedlifedata.com/resource/pubmed/id/19023589

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-5-13
pubmed:abstractText
Transient receptor potential canonical (TRPC) channels are Ca(2+)-permeable, nonselective cation channels formed by homomeric or heteromeric complexes of TRPC proteins that contain six transmembrane domains. These channels can be activated through a phospholipase-C-dependent mechanism, making them sensors for environmental cues. Their expression begins early in embryonic days and remains in adulthood. These channels have important roles in the processes of neuronal development, including neural stem cell proliferation, cerebellar granule cell survival, axon path finding, neuronal morphogenesis, and synaptogenesis. In this review, we will discuss functional implications of TRPC channels during brain development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1432-2013
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
458
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-9
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Functional roles of TRPC channels in the developing brain.
pubmed:affiliation
Graduate School, Chinese Academy of Science, 320 Yueyang Road, Shanghai 200031, China.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't