Source:http://linkedlifedata.com/resource/pubmed/id/19023200
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2008-12-18
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| pubmed:abstractText |
5-Fluorouracil (5-FU) is a widely used drug in head and neck squamous cell carcinoma (HNSCC). Thymidylate synthase (TS), which is the target enzyme of 5-FU, has been demonstrated to be a key regulatory enzyme. In this study, we examined whether TS expression is correlated with chemosensitivity to 5-FU, cell proliferation and clinical outcome in HNSCC.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1421-9794
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| pubmed:author | |
| pubmed:copyrightInfo |
(c) 2008 S. Karger AG, Basel.
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
36-41
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| pubmed:dateRevised |
2009-11-11
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| pubmed:meshHeading |
pubmed-meshheading:19023200-Antimetabolites, Antineoplastic,
pubmed-meshheading:19023200-Carcinoma, Squamous Cell,
pubmed-meshheading:19023200-Cell Proliferation,
pubmed-meshheading:19023200-Fluorouracil,
pubmed-meshheading:19023200-Head and Neck Neoplasms,
pubmed-meshheading:19023200-Humans,
pubmed-meshheading:19023200-Statistics, Nonparametric,
pubmed-meshheading:19023200-Survival Analysis,
pubmed-meshheading:19023200-Thymidylate Synthase,
pubmed-meshheading:19023200-Treatment Outcome,
pubmed-meshheading:19023200-Tumor Cells, Cultured
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Correlations between thymidylate synthase expression and chemosensitivity to 5-fluorouracil, cell proliferation and clinical outcome in head and neck squamous cell carcinoma.
|
| pubmed:affiliation |
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, Japan. yasuryuj@qent.med.kyushu-u.ac.jp
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| pubmed:publicationType |
Journal Article
|