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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-1-23
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pubmed:abstractText |
The pancreatic mass is determined by the coordinated expansion and differentiation of progenitor cells and is maintained via tight control of cell replacement rates. The basic helix-loop-helix transcription factor c-Myc is one of the main regulators of these processes in many organs. We studied the requirement of c-Myc in controlling the generation and maintenance of pancreatic mass.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1528-0012
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
309-319.e9
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pubmed:dateRevised |
2011-6-1
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pubmed:meshHeading |
pubmed-meshheading:19022256-Adipocytes,
pubmed-meshheading:19022256-Animals,
pubmed-meshheading:19022256-Cell Differentiation,
pubmed-meshheading:19022256-Cell Proliferation,
pubmed-meshheading:19022256-Epithelium,
pubmed-meshheading:19022256-Homeodomain Proteins,
pubmed-meshheading:19022256-Humans,
pubmed-meshheading:19022256-Mesoderm,
pubmed-meshheading:19022256-Mice,
pubmed-meshheading:19022256-Mice, Inbred C57BL,
pubmed-meshheading:19022256-Pancreas, Exocrine,
pubmed-meshheading:19022256-Proto-Oncogene Proteins c-myc,
pubmed-meshheading:19022256-Trans-Activators
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pubmed:year |
2009
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pubmed:articleTitle |
Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice.
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pubmed:affiliation |
Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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