Linked Life Data

19021581

Source:http://linkedlifedata.com/resource/pubmed/id/19021581

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
Pt 6
pubmed:dateCreated
2008-11-21
pubmed:abstractText
MBL (mannose-binding lectin) is a pattern recognition molecule and a component of innate immunity, the first line of the host defence system against foreign bodies and pathogens. MBL deficiency is common in humans and has been associated with immunodeficiency. We have generated mouse models of MBL deficiency in order to explore the molecular mechanisms of MBL function in disease and health. In addition to confirming findings from human clinical research, these model studies have uncovered unexpected roles of MBL and evidence of its interaction with other molecules of the innate immune system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1470-8752
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1487-90
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Lessons learned from murine models of mannose-binding lectin deficiency.
pubmed:affiliation
Programs of Developmental Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. ktakahashi1@partners.org
pubmed:publicationType
Journal Article