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rdf:type |
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lifeskim:mentions |
umls-concept:C0018787,
umls-concept:C0020564,
umls-concept:C0033414,
umls-concept:C0033554,
umls-concept:C0054450,
umls-concept:C0591833,
umls-concept:C0597357,
umls-concept:C1419063,
umls-concept:C1514559,
umls-concept:C1515877,
umls-concept:C1879547
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pubmed:issue |
2
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pubmed:dateCreated |
2009-1-15
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pubmed:abstractText |
Prostaglandin E(2) (PGE(2)) has been shown to mediate anti-ischaemic effects and cardiomyocyte hypertrophy and there is evidence for an involvement of the prostaglandin EP(3)-receptor subtype. This study focuses on the EP(3)-mediated hypertrophic action and investigates intracellular signalling pathways of the EP(3)-receptor subtype in the murine heart.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1755-3245
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
310-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19019835-Animals,
pubmed-meshheading:19019835-Calcineurin,
pubmed-meshheading:19019835-Cardiomegaly,
pubmed-meshheading:19019835-Cyclic AMP,
pubmed-meshheading:19019835-GTP-Binding Protein alpha Subunits, Gi-Go,
pubmed-meshheading:19019835-Magnetic Resonance Imaging,
pubmed-meshheading:19019835-Mice,
pubmed-meshheading:19019835-Myocytes, Cardiac,
pubmed-meshheading:19019835-Receptors, Prostaglandin E,
pubmed-meshheading:19019835-Receptors, Prostaglandin E, EP3 Subtype,
pubmed-meshheading:19019835-Signal Transduction,
pubmed-meshheading:19019835-Transgenes,
pubmed-meshheading:19019835-Ventricular Function, Left,
pubmed-meshheading:19019835-Ventricular Remodeling
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pubmed:year |
2009
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pubmed:articleTitle |
Overexpression of prostaglandin EP3 receptors activates calcineurin and promotes hypertrophy in the murine heart.
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pubmed:affiliation |
Institut für Pharmakologie und Klinische Pharmakologie, Universitätsklinikum, Heinrich-Heine-Universität, Moorenstr. 5, D-40225 Düsseldorf, Germany. meyerj@uni-duesseldorf.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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