|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2008-11-21
|
|
pubmed:abstractText |
The association between SNPs of the human OPRM1 gene encoding the micro-opioid receptor and postoperative analgesic requirements in surgical patients remains controversial. Here, we evaluate whether any of the five tag SNPs (A118G, IVS2+G691C, IVS3+G5953A, IVS3+A8449G and TAA+A2109G) representing the four linkage disequilibrium blocks of the OPRM1 gene influences postoperative analgesic requirements.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1744-8042
|
|
pubmed:author |
pubmed-author:FukudaKenichiK,
pubmed-author:HanaokaKazuoK,
pubmed-author:HasegawaJunkoJ,
pubmed-author:HayashidaMasakazuM,
pubmed-author:IdeSoichiroS,
pubmed-author:IkedaKazutakaK,
pubmed-author:KasaiShinyaS,
pubmed-author:KatohRyojiR,
pubmed-author:KogaHisashiH,
pubmed-author:KomatsuHiroshiH,
pubmed-author:NagashimaMakotoM,
pubmed-author:NishizawaDaisukeD,
pubmed-author:OgaiYasukazuY,
pubmed-author:SatohYasuoY,
pubmed-author:SoraIchiroI,
pubmed-author:TagamiMegumiM
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
9
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1605-16
|
|
pubmed:meshHeading |
pubmed-meshheading:19018716-Abdomen,
pubmed-meshheading:19018716-Adult,
pubmed-meshheading:19018716-Aged,
pubmed-meshheading:19018716-Aged, 80 and over,
pubmed-meshheading:19018716-Analgesics,
pubmed-meshheading:19018716-Analgesics, Opioid,
pubmed-meshheading:19018716-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:19018716-Digestive System Surgical Procedures,
pubmed-meshheading:19018716-Drug Therapy, Combination,
pubmed-meshheading:19018716-Female,
pubmed-meshheading:19018716-Genotype,
pubmed-meshheading:19018716-Haplotypes,
pubmed-meshheading:19018716-Humans,
pubmed-meshheading:19018716-Male,
pubmed-meshheading:19018716-Middle Aged,
pubmed-meshheading:19018716-Pain, Postoperative,
pubmed-meshheading:19018716-Polymorphism, Single Nucleotide,
pubmed-meshheading:19018716-Receptors, Opioid, mu,
pubmed-meshheading:19018716-Treatment Outcome
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Analgesic requirements after major abdominal surgery are associated with OPRM1 gene polymorphism genotype and haplotype.
|
|
pubmed:affiliation |
Division of Psychobiology, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
