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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-11-21
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pubmed:abstractText |
The dopamine receptor D4 (DRD4) 7-repeat allele and maternal smoking during pregnancy are both considered as risk factors in the aetiology of attention deficit hyperactivity disorder (ADHD), but few studies have been conducted on their interactive effects in causing ADHD. The purpose of this study is to examine the gene by environment (GxE) interaction of the DRD4 7-repeat allele and smoking during pregnancy on ADHD and oppositional behavior in families from the International Multicenter ADHD Genetics project; and further, to test the hypothesis that the direction of effect of the DRD4 7-repeat allele differs between ADHD affected and unaffected children.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-10781080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-10889550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-11872519,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-12366871,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-12777257,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-14594745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-15724142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-15950004,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16135619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16275815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16389200,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16402008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16493876,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16770765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16773450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16774975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16887023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-16894395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17071023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17075356,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17144907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17157268,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17197648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17314722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17333362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17375135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17425490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17485610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17541055,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17679637,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17718779,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-17725999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-3790875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-9618392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19017022-9634505
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1469-7610
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pubmed:author |
pubmed-author:AltinkMarieke EME,
pubmed-author:AnneyRichardR,
pubmed-author:Arias-VásquezAlejandroA,
pubmed-author:AshersonPhilipP,
pubmed-author:BrookesKeeley-JoanneKJ,
pubmed-author:BuitelaarJan KJK,
pubmed-author:BuschgensCathelijne J MCJ,
pubmed-author:ChaiY CYC,
pubmed-author:FaraoneStephen VSV,
pubmed-author:FliersEllen AEA,
pubmed-author:FrankeBarbaraB,
pubmed-author:GillMichaelM,
pubmed-author:MulliganAislingA,
pubmed-author:RommelseNanda N JNN,
pubmed-author:SergeantJoseph AJA,
pubmed-author:Slaats-WillemseDorine I EDI,
pubmed-author:Sonuga-BarkeEdmundE,
pubmed-author:ThompsonMargaretM
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pubmed:issnType |
Electronic
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1053-60
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pubmed:dateRevised |
2011-5-27
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pubmed:meshHeading |
pubmed-meshheading:19017022-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:19017022-Case-Control Studies,
pubmed-meshheading:19017022-Child,
pubmed-meshheading:19017022-Europe,
pubmed-meshheading:19017022-Female,
pubmed-meshheading:19017022-Genetic Predisposition to Disease,
pubmed-meshheading:19017022-Humans,
pubmed-meshheading:19017022-Linear Models,
pubmed-meshheading:19017022-Male,
pubmed-meshheading:19017022-Polymorphism, Genetic,
pubmed-meshheading:19017022-Pregnancy,
pubmed-meshheading:19017022-Prenatal Exposure Delayed Effects,
pubmed-meshheading:19017022-Receptors, Dopamine D4,
pubmed-meshheading:19017022-Risk Factors,
pubmed-meshheading:19017022-Sex Distribution,
pubmed-meshheading:19017022-Siblings,
pubmed-meshheading:19017022-Smoking
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pubmed:year |
2008
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pubmed:articleTitle |
The dopamine receptor D4 7-repeat allele and prenatal smoking in ADHD-affected children and their unaffected siblings: no gene-environment interaction.
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pubmed:affiliation |
Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, The Netherlands.
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