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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-19
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pubmed:abstractText |
A 57-year-old man had been diagnosed with grade IV glioblastoma multiforme and was enrolled in a trial of adoptive cellular immunotherapy. The trial involved infusion of ex vivo expanded autologous cytolytic CD8+ T cells (CTLs), genetically engineered to express the interleukin 13 zetakine gene (which encodes a receptor protein that targets these T cells to tumor cells) and the herpes simplex virus 1 thymidine kinase (HSV1 tk) suicide gene, and PET imaging reporter gene.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1743-4262
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
53-8
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pubmed:dateRevised |
2011-7-19
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pubmed:meshHeading |
pubmed-meshheading:19015650-Brain Neoplasms,
pubmed-meshheading:19015650-Fluorine Radioisotopes,
pubmed-meshheading:19015650-Gene Therapy,
pubmed-meshheading:19015650-Glioblastoma,
pubmed-meshheading:19015650-Guanine,
pubmed-meshheading:19015650-Herpesvirus 1, Human,
pubmed-meshheading:19015650-Humans,
pubmed-meshheading:19015650-Image Processing, Computer-Assisted,
pubmed-meshheading:19015650-Male,
pubmed-meshheading:19015650-Middle Aged,
pubmed-meshheading:19015650-Positron-Emission Tomography,
pubmed-meshheading:19015650-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:19015650-Thymidine Kinase
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pubmed:year |
2009
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pubmed:articleTitle |
Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma.
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pubmed:affiliation |
Multimodality Molecular Imaging Lab, Department of Radiology & Bioengineering, Stanford University, Stanford, CA, USA.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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