Source:http://linkedlifedata.com/resource/pubmed/id/19014278
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-2-5
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pubmed:abstractText |
It has been reported that patients with papillary thyroid carcinoma (PTC) have a high incidence of background Hashimoto thyroiditis (HT); however, the linkage of HT to PTC is controversial. Recent studies have shown that the prevalence of activating point mutations in BRAFV600E is much higher (73-86%) in Korea than in Western countries (29-69%), and associated with a poor prognosis in PTC. The purpose of the present study was to investigate the frequency of the BRAFV600E mutation in PTC with and without HT, and to determine clinical and pathological features that were associated with concomitant HT and PTC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1557-9077
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
137-41
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19014278-Adult,
pubmed-meshheading:19014278-Carcinoma, Papillary,
pubmed-meshheading:19014278-Cell Line, Tumor,
pubmed-meshheading:19014278-Female,
pubmed-meshheading:19014278-Hashimoto Disease,
pubmed-meshheading:19014278-Humans,
pubmed-meshheading:19014278-Korea,
pubmed-meshheading:19014278-Lymphatic Metastasis,
pubmed-meshheading:19014278-Male,
pubmed-meshheading:19014278-Middle Aged,
pubmed-meshheading:19014278-Point Mutation,
pubmed-meshheading:19014278-Prevalence,
pubmed-meshheading:19014278-Proto-Oncogene Proteins B-raf,
pubmed-meshheading:19014278-Thyroid Neoplasms
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pubmed:year |
2009
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pubmed:articleTitle |
Clinical and pathological features and the BRAF(V600E) mutation in patients with papillary thyroid carcinoma with and without concurrent Hashimoto thyroiditis.
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pubmed:affiliation |
Departments of 1Internal Medicine, Konkuk University School of Medicine, Konkuk University Medical Center, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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